
We built ReactWise to accelerate chemistry that matters. Last week at Flow Chemistry Europe, I saw exactly that happening.
One of our academic collaborators - Bernice Currie from the CSIR and the University of Pretoria - presented her work on TMTHF, a greener and safer solvent alternative to toxic petrochemical solvents like toluene.
Bernice and her co-authors developed a scalable flow route to produce TMTHF (tetramethyltetrahydrofuran) using citric acid and water - 125 grams produced at just $0.13 per gram, with a purity of 90%.
A genuinely sustainable answer to one of the most persistent challenges in industrial chemistry.
With TMTHF in hand, the team went one step further - applying it as the solvent in a photochemical reaction to demonstrate its real-world applicability.
To optimize that reaction, they used ReactWise to identify optimal conditions in just 11 experiments - the right wavelength, the right concentration, the right residence time.
The result was 89.8% conversion, without the need for a photocatalyst - a meaningful cost saving, given how expensive photocatalysts can be.
Machine learning, accelerating real chemistry, on a problem that matters.
That is exactly what we set out to build.
We learn from researchers pushing the boundaries of chemistry every day. They work with tools that help them reach answers faster. Everyone wins.
At ReactWise we are proud to support not only commercial clients but also the academic community.
We are always open to working with researchers who are tackling meaningful problems in process chemistry.
Congratulations to Bernice and her co-authors - this is exactly the kind of work worth celebrating.
If you are an academic researcher interested in collaborating with us - drop me a DM or reach out via email. We would love to hear from you.