We built ReactWise to accelerate chemistry that matters. Last week at Flow Chemistry Europe, I saw exactly that happening.

April 23, 2026

We built ReactWise to accelerate chemistry that matters. Last week at Flow Chemistry Europe, I saw exactly that happening.

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One of our academic collaborators - Bernice Currie from the CSIR and the University of Pretoria - presented her work on TMTHF, a greener and safer solvent alternative to toxic petrochemical solvents like toluene.

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Bernice and her co-authors developed a scalable flow route to produce TMTHF (tetramethyltetrahydrofuran) using citric acid and water - 125 grams produced at just $0.13 per gram, with a purity of 90%.

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A genuinely sustainable answer to one of the most persistent challenges in industrial chemistry.

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With TMTHF in hand, the team went one step further - applying it as the solvent in a photochemical reaction to demonstrate its real-world applicability.

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To optimize that reaction, they used ReactWise to identify optimal conditions in just 11 experiments - the right wavelength, the right concentration, the right residence time. 

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The result was 89.8% conversion, without the need for a photocatalyst - a meaningful cost saving, given how expensive photocatalysts can be.

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Machine learning, accelerating real chemistry, on a problem that matters.

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That is exactly what we set out to build.

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We learn from researchers pushing the boundaries of chemistry every day. They work with tools that help them reach answers faster. Everyone wins.

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At ReactWise we are proud to support not only commercial clients but also the academic community. 

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We are always open to working with researchers who are tackling meaningful problems in process chemistry.

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Congratulations to Bernice and her co-authors - this is exactly the kind of work worth celebrating.

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If you are an academic researcher interested in collaborating with us - drop me a DM or reach out via email. We would love to hear from you.

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