HTE plate design should neither feel like solving a puzzle nor be based on rigid templates. That's why we've built an automated plate designer.

March 31, 2026

HTE plate design should neither feel like solving a puzzle nor be based on rigid templates. That's why we've built an automated plate designer.

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High throughput experimentation (HTE) is transforming how chemistry teams explore reaction space.

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But as HTE scales up, one challenge keeps slowing teams down: plate design. 

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Lay out your variables by hand and you're spending hours wrestling with a spreadsheet. Use a fixed template and you're forcing your chemistry into a standardized framework.

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At @ReactWise, we took a different approach.

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Our platform combines two powerful tools to streamline your HTE workflow. 

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The AI Campaign Generator helps you define and prioritize the parameters you want to screen - solvents, catalysts, ligands, temperatures, concentrations - based on your specific goals and chemical transformations. 

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Then the HTE Plate Designer translates that intent into a structured, optimized layout across 24, 96, or 384 well plate formats.

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The result is a plate design that reflects your chemistry. 

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Layouts that are statistically sound and ready for downstream tasks like liquid or solids dosing. 

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No more wrestling with spreadsheets. No guesswork. No rework.

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Whether you're launching a catalyst screen, mapping out a ligand library, or optimizing reaction conditions, ReactWise takes you from experimental question to a ready plate design in a fraction of the time.

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Curious how it works? Drop us a pm we'd love to show you.

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